The effect of the gut microbiome on obesity: Mechanisms, interactions, and therapeutic implications: A comprehensive review

---

Review Article

Author Details : Tejashwini Kotian*, Ravi Gupta

Volume : 9, Issue : 3, Year : 2024

Article Page : 151-154

https://doi.org/10.18231/j.jdpo.2024.031

Suggest article by email

Get Permission

---

Abstract

Discovery of the gut microbiome as a crucial element in obesity. Recent research has not only linked changes to the gut microflora with development of obesity but also provided novel insights into it pathophysiology. Here we present a review paper with the latest highlights on how microbiota contribute to obesity and unravel possible molecular mechanisms by which gut microorganisms can modulate energy balance, metabolic control of body weight homeostasis and inflammation. Furthermore, we investigate the crosstalk of diet with genetics and microbiome in obesity pathophysiology as well as the gut–brain axis related to metabolic regulation, and consider future implications from this knowledge for management of obesity.
 

Keywords: Gut microbiome, Body weight, Gut-brain axis

How to cite : Kotian T, Gupta R, The effect of the gut microbiome on obesity: Mechanisms, interactions, and therapeutic implications: A comprehensive review. IP J Diagn Pathol Oncol 2024;9(3):151-154

This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.