Olfactory neuroblastoma: A rare case report

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Case Report

Author Details : Kajalba H Jhala, Kinjal Damor, Prahari Upadhyaya, Anjali Goyal*

Volume : 9, Issue : 2, Year : 2024

Article Page : 127-129

https://doi.org/10.18231/j.jdpo.2024.025

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Abstract

Olfactory neuroblastoma (ONB) is an uncommon malignant tumor of the sinonasal tract that arises from the olfactory neuroepithelium and exhibits neuroblastic differentiation. Here, we present the case of a 48-year-old woman who complained of epistaxis for 4 months, nasal obstruction, and headaches for 6 months. Upon examination, a mass was identified in the left nasal cavity and confirmed by radiological imaging. Surgical excision was performed, and the tissue specimen was sent for histopathological analysis, which confirmed the diagnosis of olfactory neuroblastoma. Immunohistochemical markers revealed focal positivity for chromogranin, synaptophysin, AE1/AE3, CK7, with a high Ki-67 index (60-70%), and negativity for S-100.
 

Keywords: Olfactory neuroblastoma, Round cells, Immunohistochemistry

How to cite : Jhala K H, Damor K, Upadhyaya P, Goyal A, Olfactory neuroblastoma: A rare case report. IP J Diagn Pathol Oncol 2024;9(2):127-129

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