Study of variants of papillary carcinoma of Thyroid with a special emphasis on NIFTP (Non-invasive Follicular Thyroid Neoplasm with Papillary like nuclear features)

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Original Article

Author Details : N Nirmala Jyoti, G V R N Krishna kanth*

Volume : 6, Issue : 3, Year : 2021

Article Page : 207-210

https://doi.org/10.18231/j.jdpo.2021.044

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Abstract

Introduction: Rapid advances have taken place in the classification of papillary thyroid neoplasms with reclassification and addition of new variants. One such change is the addition of a new entity called NIFTP (Non-invasive Follicular Thyroid Neoplasm with Papillary like nuclear features). So called recognising its non-malignant potential.
Study Design: The present study is a retrospective observational cohort study on thyroidectomy specimens collected between Jan 2018 to June 2021 focussing on variants of papillary carcinoma with special emphasis on recognising NIFTP – which has got good prognosis and is considered non-malignant.
Results: Out of the 40 cases of papillary neoplasms 36 were PTC and 4 were NIFTP. Among the PTC cases 27 were classic PTC, 4 were FVPTC (Follicular Variant of Papillary Thyroid Carcinoma) 3 were papillary microcarcinoma, 1 was Warthin like Variant of PTC and 1 was Encapsulated PTC.
Conclusion: The Study concludes that special vigilance is required in strictly adhering to the criteria proposed by new 2017 WHO classification of Papillary tumours. Recognising NIFTP as it is a nonmalignant entity should be given due importance.

Keywords: Papillary Thyroid Carcinoma (PTC), Risk stratification, Variants of PTC, Non­invasive follicular

How to cite : Jyoti N N, Kanth G V R N K, Study of variants of papillary carcinoma of Thyroid with a special emphasis on NIFTP (Non-invasive Follicular Thyroid Neoplasm with Papillary like nuclear features). IP J Diagn Pathol Oncol 2021;6(3):207-210

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