Spectrum of neoplastic and non neoplastic skin lesions: A histopathological institutional study

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Original Article

Author Details : Deepthi K.N, Shilpa Karamchedu*, Saritha G

Volume : 5, Issue : 1, Year : 2020

Article Page : 25-29

https://doi.org/10.18231/j.jdpo.2020.005

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Abstract

Introduction: Skin lesions are complex due to wide range of neoplastic and non-neoplastic lesions.
Several studies showed high prevalence of skin disorders in developing countries. Clinical presentation
is restricted to hyperpigmentation, hypopigmentation, macules, papules and nodules but histopathology is
highly variable. Accurate diagnosis is needed due to disease specific treatment and prognosis. Aim of the
study is to evaluate different histopathological patterns of skin lesions for accurate diagnosis and to analyze
age and sex distribution of skin lesions.
Materials and Methods: The study included a total number of 125 skin biopsies from July 2018
to June 2019 sent for histopathological examination to pathology department, SVS Medical College,
Mahabubnagar, Telangana, India.
Results: In our study total 125 cases were analyzed. Out of which majority of the lesions (38.97 %) were in
the age group of 21-40 years. Present study showed cutaneous cysts being the most common non-neoplastic
lesion. In malignant tumors, out of 20 cases, 50% cases were Squamous cell carcinoma followed by basal
cell carcinoma (30%).
Conclusion: Even though clinical features are few biopsy shows varied pathology and it is crucial for
accurate diagnosis and differential diagnosis of skin lesions. Skin biopsy is a simple, inexpensive and
gold standard method for definitive diagnosis and treatment of skin lesions. In the present study, n on
neoplastic lesions are more common than neoplastic skin lesions. Non neoplastic lesions more common
in younger males of 21-40 yrs and neoplastic lesions in older age group. Epidermal cyst is most common
non neoplastic lesion followed by trichilemmal cyst. Squamous papilloma is the most common benign
neoplasm & Squamous cell carcinoma is the most common malignant neoplasm.

Keywords: Neoplastic skin lesions, Epidermal cyst, Squamous cell carcinoma, Benign malignant neoplasm

How to cite : K.n D, Karamchedu S, Saritha G, Spectrum of neoplastic and non neoplastic skin lesions: A histopathological institutional study. IP J Diagn Pathol Oncol 2020;5(1):25-29

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