Spectrum of pathological lesions in nephrectomy specimens: A study of 50 lesions

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Author Details : Shirish S Chandanwale*, Piyusha Naragude, Madhuri Singh, Gore Charusheela, Aishwarya Desai

Volume : 4, Issue : 4, Year : 2019

Article Page : 292-298

https://doi.org/10.18231/j.jdpo.2019.061

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Abstract

Introduction: Kidneys are involved in variety of pathological processes. Renal diseases are an important
cause of morbidity worldwide. Chronic pyelonephritis and its variants still continue to be the leading cause
of nephrectomies in developing country like India. In some developed countries, neoplastic lesion is the
commonest indication for nephrectomy.
Aim: The study is carried out to study the frequency of various neoplastic and non-neoplastic lesions in
nephrectomy specimens and to study histomorphological features in a teaching hospital.
Materials and Methods: The t otal of 50 nephrectomy cases were studied. Detailed clinical finding were
collected from case sheets. Detailed gross findings and histomorphological features were studied.
Results: Out of 50 lesions 35 were non neoplastic and 15 were neoplastic. Out of 35 nephrectomy lesions,
32 cases were of chronic pyelonephritis and males (n=18) were commonly affected than female (n=14).
Out of 15 neoplastic lesions majority(n=12) were renal cell carcinoma and most commonly (n=12) involved
males.
Conclusion: In developing country like India pyelonephritis is the commonest cause of nephrectomy.
Better treatment modalities of inflammatory lesions of kidney in the develop ing countries will reduce the
rate of nephrectomies.

Keywords: Kidney, Carcinoma, Chronic, Pyelonephritis.

How to cite : Chandanwale S S, Naragude P, Singh M, Charusheela G, Desai A, Spectrum of pathological lesions in nephrectomy specimens: A study of 50 lesions. IP J Diagn Pathol Oncol 2019;4(4):292-298

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