Pleomorphic adenoma of the hard palate: A case review with histopathological and immunohistochemical correlation

• Author Details:   
• Neha Kamboj ^*

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Pleomorphic adenoma is the most frequently encountered tumor of the salivary glands, with a strong predilection for the parotid gland. It usually manifests as a slowly enlarging, non-tender swelling. This neoplasm exhibits a dual cellular composition, incorporating both epithelial elements (including ductal and myoepithelial cells) and a stromal component that may appear mucoid, cartilaginous, or fibrous in nature. While it is a benign lesion, there is a possibility of recurrence, particularly after incomplete excision, and in rare instances, it may undergo malignant transformation. Therefore, precise histopathological diagnosis and adequate surgical removal are crucial for effective management and to minimize future complications.

Keywords: Pleomorphic adenoma, Neoplasm, Salivary glands, Benign mixed tumor.