Coexistence of follicular variant of papillary thyroid carcinoma and oncocytic adenoma on the background of Hashimoto’s thyroiditis: Case report

• Author Details:   
• Vaanika Kaira
• Jocelyn Sara Paul
• Vibha R Vyas ^*
• Majal Shah
• Isha Sharma

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Papillary thyroid carcinoma (PTC) is the most common histologic type of thyroid cancer comprising of 80–90% of all subtypes with female predominance. Hashimoto’s thyroiditis (HT), also synonymous with chronic autoimmune thyroiditis and chronic lymphocytic thyroiditis, is an autoimmune disease characterized by immune destruction of thyroid cells mediated via cell and antibody dependant immune processes. Dailey et al. first described the association between PTC and HT in 1955. Approximately 30% of PTC have HT in their background. Several studies have reported HT as a risk factor for the development of PTC. Oncocytic adenomas (OA) comprise 10-15% of thyroid nodules and more common in men. We are reporting this case of 29 year old female having multifocal infiltrative follicular variant of PTC and Oncocytic adenoma with marked cytological atypia in the background of HT as it is very rare to encounter this coexistence except in the context of tumour syndromes.

Keywords: Papillary carcinoma, Oncocytic, Adenoma, Hashimoto’s thyroiditis.